Jian Jin, Ph.D.

Dr. Jian Jin is an internationally recognized medicinal chemist with more than 25 years of experience in small-molecule drug discovery. He is currently the Mount Sinai Endowed Professor in Therapeutics Discovery and Director of the Mount Sinai Center for Therapeutics Discovery at Icahn School of Medicine at Mount Sinai (Mount Sinai). Dr. Jin is also a tenured professor in Departments of Pharmacological Sciences, Oncological Sciences and Neuroscience, and a Co-Leader of the Cancer Clinical Investigation Program at The Tisch Cancer Institute at Mount Sinai. Dr. Jin’s laboratory is a leader in discovering selective inhibitors of histone methyltransferases, biased ligands of G protein-coupled receptors, and novel degraders targeting oncogenic proteins. Dr. Jin received a Bachelor’s of Science degree in chemistry from the University of Science and Technology of China in 1991 and a PhD in organic chemistry from the Pennsylvania State University in 1997, and completed a post-doctoral training at the Ohio State University. Dr. Jin was an Associate Professor in the Division of Chemical Biology and Medicinal Chemistry at the University of North Carolina at Chapel Hill (UNC) and Associate Director of Medicinal Chemistry in the Center for Integrative Chemical Biology and Drug Discovery at UNC from 2008 to 2014. Dr. Jin was recruited to Mount Sinai as a professor with tenure in 2014. Dr. Jin has published >200 peer-reviewed papers and is an inventor of >70 issued U.S. patents and published international patent applications. In particular, Dr. Jin is one of several inventors of Daprodustat, a hypoxia-inducible factor (HIF) prolyl hydroxylase small-molecule inhibitor, which has been approved in the U.S. and Japan as an oral medication for the treatment of anemia caused by chronic kidney disease. Dr. Jin was elected to the National Academy of Inventors (NAI) as an NAI Fellow in 2022.