Director of Cancer Biology

Shanghai, China

Company Overview

Cullgen is a privately held biopharmaceutical company dedicated to the development of first-in-class new chemical entities (NCEs) for the treatment of diseases lacking effective therapeutic approaches. We are developing our proprietary technology platform, ubiquitin-mediated, small molecule-induced target elimination technology, (uSMITE™), based on recent advances in the science of protein degradation. We are leveraging our uSMITETM platform to develop degrader molecules for the treatment of cancer through selectively depleting undruggable proteins in malignant tissues.

Fueled by emerging science and coached by a strong management team, Cullgen has been growing rapidly since its inception in 2018. We welcome self-driven and innovative scientists to join our team and assist us in the development of targeted protein degraders for the treatment of cancer and other diseases in which there is a high unmet need. Cullgen provides a family-like atmosphere that encourages employees to demonstrate their talents and leadership skills. Working as a team, we have been able to quickly advance candidate molecules towards the clinic, and now anticipate filing of our first IND in 2021.

Position Summary

We are seeking a highly motivated and innovative cancer biologist to join our Department of Discovery Medicine. The successful candidate is expected to serve as a scientific and team leader for our early discovery programs and will have a proven track record of accomplishment in both science and project management. Principle duties of this position requires scientific, technical, and managerial skills. Relevant similar experiences in both industry and academia are appreciated. A solid background in cancer biology is highly desired. This job position will be located at our R&D center in Shanghai, China.

Key Responsibilities:

  • Lead a multi-disciplinary team to develop novel protein degraders.

  • Oversee drug discovery efforts through the entire pre-clinical process from target identification to nomination of clinical candidates.

  • Drive expansion of Cullgen’s technology platforms.

  • Maintain & grow knowledge of current & latest scientific advances in related disciplines.

  • Ability to create and deliver compelling scientific presentations and reports for internal and external audiences.

  • Manage and prioritize multiple programs to ensure timelines are met.

  • Provide strong leadership and mentorship for project teams.

Qualifications:

  • PhD in biochemistry, cancer biology, pharmacology, or related disciplines with >10 years of industrial / academic experience.

  • A deep understanding of cancer biology and drug discovery.

  • Proven scientific knowledge in drug discovery with the ability to integrate biology and pharmacology.

  • A demonstrated track record of achievements as shown by strong publications and / or patents.

  • Exceptional oral and written communication skills for scientific and non-scientific audiences through presentations and written reports.

  • Ability to guide and mentor junior scientists and to work collaboratively in a multi-disciplinary, multi-national setting.

Experience:

  • Drug Discovery: 5 years

  • Cancer Biology: 10 years

Education:

  • Doctorate

If interested, please send cover letter with resume to: careers@cullgen.com